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J.A. Joseph, B. Shukitt-Hale, J. McEwen,B.M. Rabin. CNS-induced deficits of heavy particle irradiation in space: the aging connection. Adv. Space Res., 25(10), 2057-64, 2000.

2. J.E. Trosko. Hierarchical and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents. Environ Health Perspect, 106 Suppl 1, 331-9, 1998.

3. L. Satta, G. Augusti-Tocco, R. Ceccarelli, A. Esposito, M. Fiore, P. Paggi, I. Poggesi, R. Ricordy, G. Scarsella, E. Cundari. Low environmental radiation background impairs biological defence of the yeast Saccharomyces cerevisiae to chemical radiomimetic agents. Mut Res, 347(3-4), 129-33, 1995.

4. L. Satta, F. Antonelli, M. Belli, O. Sapora, G. Simone, E. Sorrentino, M.A. Tabocchini, F. Amicarelli, C. Ara, M.P. Ceru, S. Colafarina, L. Conti Devirgiliis, A. De Marco, M. Balata, A. Falgiani, S. Nisi . Influence of a low background radiation environment on biochemical and biological responses in V79 cells. Radiat Environ Biophys, 41(3), 217-24, 2002.

5. T. Ohnishi, A. Takahashi, K. Ohnishi. Biological effects of space radiation. Biol Sci. Space 2001; 15 Suppl: S203-10.

6. T. Ohnishi, A. Takahashi, K. Ohnishi, H. Matsumoto. DNA damage formation and p53 accumulation in mammalian cells exposed to the space environment. Biol Sci. Space, 13(2), 82-7, 1999.

7. K. George, M. Durante, H. Wu, V. Willingham, G. Badhwar, F.A. Cucinotta. Chromosome aberrations in the blood lymphocytes of astronauts after space flight. Radiat Res, 156(6), 731-8, 2001.

8. N. Dousset, J.P. Moatti, N. Moatti, M. Degre, B. Eche, G. Gasset, R. Tixador. Influence of the environment in space on the biochemical characteristics of human low density lipoproteins. Free Radic Res, 24(1), 69-74, 1996.

9. D.R. Morrison. Cellular changes in microgravity and the design of space radiation experiments. Adv Space Res, 14(10), 1005-19, 1994.

10. L. Zamai, B. Canonico, A. Gritzapis, F. Luchetti, C. Felici, M. Della Felice, L. Margomenou, M. Papamichail, J.W. Gratama, S. Papa. Intracellular detection of Bcl-2 and p53 proteins by flow cytometry: comparison of monoclonal antibodies and sample preparation protocols. J Biol Regul Homeost Agents,16(4), 289-302, 2002.

11. C.A. Kleeberger, R.H. Lyles, J.B. Margolick, C.R. Rinaldo, J.P. Phair, J.V. Giorgi. Viability and recovery of peripheral blood mononuclear cells cryopreserved for up to 12 years in a multicenter study. Clin Diagn Lab Immunol, 6 (1), 14-19, 1999.

12. E. Garman. ‘Cool' crystals: macromolecular cryocrystallography and radiation damage. Curr Opin Struct Biol 13, 545-551, 2003.

13. C.R. Valeri, L.E. Pivacek, G.P. Cassidy, G. Ragno. In vitro and in vivo measurements of gamma-radiated, frozen, glycerolized RBCs. Transfusion, 41, 545-549, 2001.

14. L. Zamai, E. Falcieri, G. Marhefka, M. Vitale. Supravital exposure to propidium iodide identifies apoptotic cells in the absence of nucleosomal DNA fragmentation. Cytometry, 23, 303-311, 1996.

15. E.Falcieri, L.Zamai , S.Santi, C.Cinti, P.Gobbi, D.Bosco, A.Cataldi, C. Betts, M.Vitale. The behaviour of nuclear domains in the course of apoptosis . Histochemistry, 102, 221-231, 1994.

16. L. Zamai, E. Falcieri, P. Gobbi, S. Santi, M. Falconi, G. Marhefka, M. Vitale. ANTI-BRDU labelling of newly synthesized DNA in HL-60 cells triggered to apoptosis. Cytometry, 25, 324-332, 1996.

17. L. Zamai, B. Canonico, F. Luchetti, P. Ferri, E. Melloni, L. Guidotti, A. Cappellini, G.Cutroneo, M. Vitale, and S. Papa. Supravital exposure to propidium iodide identifies apoptosis on adherent cells. Cytometry, 44, 57-64, 2001.

18. L. Zamai, E. Falcieri, G. Zauli, A. Castaldi, M. Vitale. Optimal detection of apoptosis by flow cytometry depends on cell morphology. Cytometry, 14, 891-897, 1993.

19. L. Zamai, M. Ahmad, I.M. Bennett, L. Azzoni, E.S. Alnemri, and B. Perussia. Natural Killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J.Exp.Med . , 188 (2), 2375-2380, 1998.

20. L. Zamai, P. Secchiero, S. Pierpaoli, A. Bassini, S. Papa, E.S. Alnemri, L. Guidotti, M. Vitale, and G. Zauli. TNF-related apoptosis-inducing ligand (TRAIL) as a negative regulator of normal human erythropoiesis. Blood, 95, 3716-3724, 2000.

21. L. Zamai, S. Burattini, F. Luchetti, B. Canonico, P. Ferri, E. Melloni, A Gonelli, L. Guidotti, S. Papa, E. Falcieri. In vitro apoptotic cell death during erythroid differentiation. Apoptosis, 9(2), 235-246, 2004.

22. J.W. Gratama, A. Orfao, D. Barnett, B. Brando, A. Huber, G. Janossy, H.E. Johnsen, M. Keeney, G.E. Marti, F. Preijers, G. Rothe, S. Serke, D.R. Sutherland, C.E. Van der Schoot,G. Schmitz, S. Papa . Flow cytometric enumeration of CD34+ hematopoietic stem and progenitor cells. European Working Group on Clinical Cell Analysis. Cytometry, 34(3), 128-42, 1998.

23. J.W. Gratama, M. Keeney, D.R. Sutherland, S. Papa. The real CD34+ events: simplicity versus accuracy and flexibility. Exp Hematol, 27(6), 975-7, 1999.

24. D. Barnett, V. Granger, J. Kraan, L. Whitby, J.T. Reilly, S. Papa, J.W. Gratama. Reduction of intra- and inter-laboratory variation in CD34+ stem cells enumeration by the use of stable test material, standard protocols and targeted training. Brit.J.Hematol, 108, 784-792, 2000.

25. L. Zamai, R. Rana, G. Mazzotti, L. Centurione, R. Di Pietro, M. Vitale. L ymphocyte binding to K562 cells: effect of target cell irradiation and correlation with ICAM-1 and LFA-3 expression. Eur. J. Histochem., 38, 53-60, 1994.

26. L. Zamai, G. Zauli, A. Bavelloni, S. Marmiroli, A. Cataldi, G. Weber, M. Vitale. Tiazofurin induces a down-modulation of ICAM-1 expression on K562 target cells impairing NK adhesion and killing. Cell. Immunol., 164, 100-104, 1995.

27. M.J. Loza, L. Zamai, L. Azzoni, E. Rosati, and B. Perussia . E xpression of type 1 (IFN-gamma) and type 2 (IL-13, IL-5) cytokines at distinct stages of NK cell differentiation from progenitor cells. Blood, 99, 1273-1281, 2002.

28. R. Di Pietro, L. Centurione, E. Santavenere, M.A. Centurione, G. Sanita Di Toppi, L. Zamai, R. Rana. Ionizing radiation-induced apoptosis and DNA repair in murine erythroleukemia cells. Scanning Microscopy, 10 (1), 253-259, 1996.

29. R.Di Pietro, P. Secchiero, R. Rana, D. Gibellini, G. Visani, K. Bemis, L. Zamai, S. Miscia and G. Zauli. Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to TNF-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity via selective up-regulation of TRAIL-R1. Blood, 97, 2596-2603, 2001.

30. B. Canonico, L. Zamai, S. Burattini, V. Granger, F. Mannello, P. Gobbi, C. Felici, E. Falcieri, J.T. Reilly, D. Barnett, S. Papa. Evaluation of leukocyte stabilisation in transfix-treated blood samples by flow cytometry and transmission electron microscopy. J Immunol Methods, 295(1-2), 67-78, 2004.

31. D. Barnett, V. Granger, P. Mayr, I. Storie, G.A. Wilson, J.T. Reilly. Evaluation of a novel stable whole blood quality control material for lymphocyte subset analysis: results from the UK NEQAS immune monitoring scheme. Cytometry, 26, 216-22,1996.


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