- From Fiumicino Airport follow the signs for Rome.
- After about 13 km. take the ramp Naples/L’Aquila (on the right) and follow the signs for the motorway L’Aquila-Teramo/Pescara/Firenze for about 30 km.
- Leave the highway at the exit 14 and take the motorway A24 L’Aquila-Teramo until Assergi.
- After the tollgate turn on the right and follow the signs for the Gran Sasso National Laboratories.